This paper analyzes the roles of health goods and services markets within the regional integration process. It is a known fact that the consolidation of integrated markets is slower regarding social goods and services (as health and education) than among other goods and services (e.g. durable consumption goods). The paper discusses the nature of the health sector and its global dimension, showing the peculiar features of health goods and services marked by economic complexity and (according to Arrow) information asymmetry. Despite that, the paper emphasizes old and new reasons that place Health as a pre-requisite to commercial integration. It approaches the role played by the State in health financing, provision and regulation and the commercial integration process. Moreover, it brings relevant concepts on the topic studied, like the factors that lead to regional public health financing, the concept of Regional Public Good and its use in the health sector, additionally to the concerns related with health care reciprocity among countries. Finally, it approaches health markets regional integration in the European Union, NAFTA, and Mercosur.